Publications

We believe that clear communication of research results is a critical part of health economics and outcomes research (HEOR) and policy analysis, and the best way to communicate results is through peer-reviewed publications. Avalon researchers and consultants have published their research in a wide range of peer-reviewed journals and books, covering topics across all four of Avalon’s practice areas. This list below provides a partial list of publications.

Publication List

2024 Publications

Treatment discontinuation in adults with atypical hemolytic uremic syndrome (aHUS): a qualitative study of international experts’ perspectives with associated cost-consequence analysis. 2024
2023 Publications

Cost-effectiveness analysis of LungLB for the clinical management of patients with indeterminate pulmonary nodules. 2023
2022 Publications

Modelling the global economic costs of tobacco product waste

Beyond 10-Year Risk: A Cost-Effectiveness Analysis of Statins for the Primary Prevention of Cardiovascular Disease

Consolidated Health Economic Evaluation Reporting Standards 2022 (CHEERS 2022) Statement: Updated Reporting Guidance for Health Economic Evaluations

Challenges for decision-makers when assessing within-class comparative effectiveness: the case of anticoagulation therapy for atrial fibrillation

Cost impact analysis of novel host-response diagnostic for patients with community-acquired pneumonia in the emergency department
2021 Publications

Reimbursement for genetic variant reinterpretation: five questions payers should ask

Developing a Framework for the Health Technology Assessment of Histology-independent Precision Oncology Therapies

Genetic Variant Reinterpretation: Economic and Population Health Management Challenges

A Cost-Offset Analysis of the Roxadustat Incident Dialysis-Dependent Global Phase 3 Program: A US Healthcare Perspective

Mendelian randomization: estimation of inpatient hospital costs attributable to obesity

Count the cost of disability caused by COVID-19

Estimating (quality-adjusted) life-year losses associated with deaths: With application to COVID-19

Cost-impact analysis of baroreflex activation therapy in chronic heart failure patients in the United States

An Attribution of Value Framework for Combination Therapies
2020 Publications

Cost Impact Model of a Novel Multi-mRNA Host Response Assay for Diagnosis and Risk Assessment of Acute Respiratory Tract Infections and Sepsis in the Emergency Department

Covariate-adjusted Analysis of the Phase 3 REFLECT Study of Lenvatinib Versus Sorafenib in the Treatment of Unresectable Hepatocellular Carcinoma.

Application of a simple point-of-care test to reduce UK healthcare costs and adverse events in outpatient acute respiratory infections.

Real-world evidence on clinical outcomes in immune thrombocytopenia treated with thrombopoietin receptor agonists.

Online Simulation Model to Estimate the Total Costs of Tobacco Product Waste in Large U.S. Cities.
2019 Publications

Economic evaluation of cardiac magnetic resonance with Fast-SENC in the diagnosis and management of early heart failure.

Cost-impact of cardiac magnetic resonance imaging with Fast-SENC compared to SPECT in the diagnosis of coronary artery disease in the U.S.

Economic evaluation of passive monitoring technology for seniors.

3-month versus 6-month adjuvant chemotherapy for patients with high-risk stage II and III colorectal cancer: 3-year follow-up of the SCOT non-inferiority RCT.

Comparison of health state utility estimates from instrument-based and vignette-based methods: a case study in kidney disease.

Economic evaluation of passive monitoring technology for seniors.

A quality of life mapping function developed from a grass pollen sublingual immunotherapy trial to a tree pollen sublingual immunotherapy trial.

Enhancing Health Through Access to Nature: How Effective are Interventions in Woodlands in Deprived Urban Communities? A Quasi-experimental Study in Scotland, UK

The Economics of Reasonable Value and the Valuation of Medical Losses.

What is the Reasonable Value of Future Medical Care?
2018 Publications

SCOT: a comparison of cost-effectiveness from a large randomised phase III trial of two durations of adjuvant Oxaliplatin combination chemotherapy for colorectal cancer.

Effect of theophylline as adjunct to inhaled corticosteroids on exacerbations in patients with COPD: a randomized clinical trial.

Behavioural activation versus guided self-help for depression in adults with learning disabilities: the BeatIt RCT.

Comparison between high-sensitivity cardiac troponin T and cardiac troponin I in a large general population cohort.

Long-term weight loss following a randomised controlled trial of a weight management programme for men delivered through professional football clubs: the Football Fans in Training follow-up study.

A decision-analytic model to assess the cost-effectiveness of etelcalcetide vs. cinacalcet.

Enhancing the value of the ASCO value framework.

3 versus 6 months of adjuvant oxaliplatin-fluoropyrimidine combination therapy for colorectal cancer (SCOT): an international, randomised, phase 3, non-inferiority trial.

Rationale and design of the British Heart Foundation (BHF) Coronary Microvascular Angina (CorMicA) stratified medicine clinical trial.

A decision framework for treating chronic immune thrombocytopenia with thrombopoietin receptor agonists.

High-Sensitivity Troponin T and Incident Heart Failure in Older Men: British Regional Heart Study.

Highest risk-highest benefit’ strategy: a pragmatic, cost-effective approach to targeting use of PCSK9 inhibitor therapies.

Long-term weight loss trajectories following participation in a randomised controlled trial of a weight management programme for men delivered through professional football clubs: A longitudinal cohort study and economic evaluation.

The feasibility of a randomised-controlled trial to compare the cost-effectiveness of palliative cardiology or usual care in people with advanced heart failure: two exploratory prospective cohorts.

Cost-effectiveness of sacubitril/valsartan in the treatment of heart failure with reduced ejection fraction.

Cost-effectiveness of umeclidinium compared with tiotropium and glycopyrronium as monotherapy for chronic obstructive pulmonary disease: a UK perspective.

EQ-5D-5L: Smaller steps but a major step change?

Estimating the Long-Term Outcomes Associated With ImmunoOncology Therapies: Challenges and Approaches for Overall Survival Extrapolations.
2017 Publications

Economic evaluation of procalcitonin-guided antibiotic therapy in acute respiratory infections: a Chinese hospital system perspective.

A Methodological Approach for Measuring the Impact of HTA.

Assessing the impact of state “opt-out” policy on access to and costs of surgeries and other procedures requiring anesthesia services.

Comparison of behavioural activation with guided self-help for treatment of depression in adults with intellectual disabilities: a randomised controlled trial

Systematic scoping review of patients’ perceived needs of health services for osteoporosis

Evaluation of Health in Pregnancy grants in Scotland: a natural experiment using routine data

Models of Care for musculoskeletal pain conditions: driving change to improve outcomes

Protocol for an economic evaluation of the randomised controlled trial of culprit lesion only PCI versus immediate multivessel PCI in acute myocardial infarction complicated by cardiogenic shock: CULPRIT-SHOCK trial.

End user and implementer experiences of mHealth technologies for noncommunicable chronic disease management in young adults: a qualitative systematic review protocol.

Health-related quality-of-life implications of cardiovascular events in individuals with type 2 diabetes mellitus: A subanalysis from the Saxagliptin Assessment of Vascular Outcomes Recorded in Patients with Diabetes Mellitus (SAVOR)-TIMI 53 trial

An analysis of procedures that affect response variability

PATHway I: design and rationale for the investigation of the feasibility, clinical effectiveness and cost-effectiveness of a technology-enabled cardiac rehabilitation platform

Development of a Conceptual Model of Disease Progression for Use in Economic Modeling of Chronic Obstructive Pulmonary Disease

Statistical Modeling of Disease Progression for Chronic Obstructive Pulmonary Disease Using Data from the ECLIPSE Study

Cost-effectiveness Analysis in R Using a Multi-state Modeling Survival Analysis Framework: A Tutorial.

Development of the Galaxy Chronic Obstructive Pulmonary Disease (COPD) Model Using Data from ECLIPSE: Internal Validation of a Linked-Equations Cohort Model

Outcomes of Surgeries Performed in Physician Offices Compared With Ambulatory Surgery Centers and Hospital Outpatient Departments in Florida.

Detection in blood of autoantibodies to tumour antigens as a case-finding method in lung cancer using the EarlyCDT®-Lung Test (ECLS): study protocol for a randomized controlled trial.

Health impact assessment of the UK soft drinks industry levy: a comparative risk assessment modelling study
2016 Publications

Cost impact of unexpected disposition after orthopedic ambulatory surgery associated with category of anesthesia provider.

The International Decision Support Initiative Reference Case for Economic Evaluation: An Aid to Thought

A View from the Bridge: Health Economic Evaluation – A Value-Based Framework?

Analyzing Health-Related Quality of Life in the EVOLVE Trial: The Joint Impact of Treatment and Clinical Events

The SCottish Alcoholic Liver disease Evaluation: A Population-Level Matched Cohort Study of Hospital-Based Costs, 1991-2011

Close Contact Casting vs Surgery for Initial Treatment of Unstable Ankle Fractures in Older Adults: A Randomized Clinical Trial

Patient Heterogeneity in Health Economic Decision Models for Chronic Obstructive Pulmonary Disease: Are Current Models Suitable to Evaluate Personalized Medicine?

Estimating Health-State Utility for Economic Models in Clinical Studies: An ISPOR Good Research Practices Task Force Report

Unrelated Future Costs and Unrelated Future Benefits: Reflections on NICE Guide to the Methods of Technology Appraisal

Determination of the most appropriate method for extrapolating overall survival data from a placebo-controlled clinical trial of lenvatinib for progressive, radioiodine-refractory differentiated thyroid cancer

A cardiovascular disease policy model: part 2-preparing for economic evaluation and to assess health inequalities

Tools for Economic Analysis of Patient Management Interventions in Heart Failure Cost-Effectiveness Model: A Web-based program designed to evaluate the cost-effectiveness of disease management programs in heart failure

Are financial incentives cost-effective to support smoking cessation during pregnancy?
2015 Publications

In-office magnetic resonance imaging (MRI) equipment ownership and MRI volume among Medicare patients in orthopedic practices.

Economic evaluation of procalcitonin-guided antibiotic therapy in acute respiratory infections: a US health system perspective.

The Economics Of Critical Care Diagnostics: The Case Of Procalcitonin-Guided Care In Treatment Of Acute Respiratory Infection In The U.S.

Operationalising the capability approach as an outcome measure in public health: The development of the OCAP-18

Decision analytic cost-effectiveness model to compare prostate cryotherapy to androgen deprivation therapy for treatment of radiation recurrent prostate cancer.

Hospital Expenditure at the End-of-Life: What Are the Impacts of Health Status and Health Risks?

A cardiovascular disease policy model that predicts life expectancy taking into account socioeconomic deprivation.

Temporal trends and risk factors for readmission for infections, gastrointestinal and immobility complications after an incident hospitalisation for stroke in Scotland between 1997 and 2005.
2014 Publications

Can Improved Treatment of Allergic Rhinitis Improve Workplace Productivity? The Role of Intranasal Formulation of Azelastine Hydrochloride and Fluticasone Propionate (Dymista).

The progressivity of health-care financing in Kenya.

Methods for Specifying the Target Difference in a Randomised Controlled Trial: The Difference ELicitation in TriAls (DELTA) Systematic Review.

Assessing methods to specify the target difference for a randomised controlled trial: DELTA (Difference ELicitation in TriAls) review.

Projecting long-term graft and patient survival after transplantation.

Questionnaire to assess relevance and credibility of modeling studies for informing health care decision making: an ISPOR-AMCP-NPC Good Practice Task Force report.
2013 Publications

Population ageing and healthcare expenditure projections: new evidence from a time to death approach.

A patient-centred approach to estimate total annual healthcare cost by body mass index in the UK Counterweight programme.

How effective is the Forestry Commission Scotland’s woodland improvement programme–‘Woods In and Around Towns’ (WIAT)–at improving psychological well-being in deprived urban communities? A quasi-experimental study

Time trends in 30 day case-fatality following hospitalisation for asthma in adults in Scotland: a retrospective cohort study from 1981 to 2009.

Prognosis Research Strategy (PROGRESS) 2: prognostic factor research.
2012 Publications

Organizational boundaries of medical practice: the case of physician ownership of ancillary services.
2011 Publications

Tobacco litter costs and public policy: a framework and methodology for considering the use of fees to offset abatement costs.

Effects of health savings account-eligible plans on utilization and expenditures.
2010 Publications

Outcome measurement in economic evaluations of public health interventions: a role for the capability approach?

International comparison of comparative effectiveness research in five jurisdictions: insights for the US.
2009 Publications

Converting to critical access status: how does it affect rural hospitals’ financial performance?

Factors associated with Iowa rural hospitals’ decision to convert to critical access hospital status.
2008 Publications

Cost effectiveness of a point-of-care test for adenoviral conjunctivitis.

The economics of specialty hospitals.

Factors associated with Iowa rural hospitals’ decision to convert to critical access hospital status.
2007 Publications

Effects of specialty hospitals on the financial performance of general hospitals, 1997-2004.

Effect of critical access hospital conversion on patient safety.
2006 Publications

Clinical practice guidelines and organizational adaptation: a framework for analyzing economic effects.
2005 Publications

Implementation of hospital computerized physician order entry systems in a rural state: feasibility and financial impact.
2004 Publications

What would be the effect of referral to high-volume hospitals in a largely rural state?

Publications

Publication List

2024 Publications

2023 Publications

2022 Publications

2021 Publications

2020 Publications

2019 Publications

2018 Publications

2017 Publications

2016 Publications

2015 Publications

2014 Publications

2013 Publications

2012 Publications

2011 Publications

2010 Publications

2009 Publications

2008 Publications

2007 Publications

2006 Publications

2005 Publications

2004 Publications