Publications

Publications

We believe that clear communication of research results is a critical part of health economics and outcomes research (HEOR) and policy analysis, and the best way to communicate results is through peer-reviewed publications. Avalon researchers and consultants have published their research in a wide range of peer-reviewed journals and books, covering topics across all four of Avalon’s practice areas. This list below provides a partial list of publications.

Journals Include

  • Journal of the American Medical Association
  • Medical Care Research and Review
  • International Journal of Healthcare Finance and Economics
  • Tobacco Control
  • Health Economics Review
  • Health Affairs
  • Inquiry
  • Health Services Research
  • Review of Industrial Organization
  • International Journal of Technology Assessment in Health Care
  • American Journal of Medical Science
  • Prevention Science
  • Health Care Financing Review
  • Value in Health
  • American Journal of Managed Care
  • Journal of Managed Care Pharmacy
  • Health Economics
  • Review of Economics and Statistics
  • Medical Care

Publication List

Estimating the Long-Term Outcomes Associated With ImmunoOncology Therapies: Challenges and Approaches for Overall Survival Extrapolations. 2018

Health impact assessment of the UK soft drinks industry levy: a comparative risk assessment modelling study 2017

Comparison of behavioural activation with guided self-help for treatment of depression in adults with intellectual disabilities: a randomised controlled trial 2017

Systematic scoping review of patients’ perceived needs of health services for osteoporosis 2017

Evaluation of Health in Pregnancy grants in Scotland: a natural experiment using routine data 2017

Models of Care for musculoskeletal pain conditions: driving change to improve outcomes 2017

End user and implementer experiences of mHealth technologies for noncommunicable chronic disease management in young adults: a qualitative systematic review protocol. 2017

Protocol for an economic evaluation of the randomised controlled trial of culprit lesion only PCI versus immediate multivessel PCI in acute myocardial infarction complicated by cardiogenic shock: CULPRIT-SHOCK trial. 2017

Health-related quality-of-life implications of cardiovascular events in individuals with type 2 diabetes mellitus: A subanalysis from the Saxagliptin Assessment of Vascular Outcomes Recorded in Patients with Diabetes Mellitus (SAVOR)-TIMI 53 trial 2017

An analysis of procedures that affect response variability 2017 July

PATHway I: design and rationale for the investigation of the feasibility, clinical effectiveness and cost-effectiveness of a technology-enabled cardiac rehabilitation platform 2017

Development of a Conceptual Model of Disease Progression for Use in Economic Modeling of Chronic Obstructive Pulmonary Disease 2017

Statistical Modeling of Disease Progression for Chronic Obstructive Pulmonary Disease Using Data from the ECLIPSE Study 2017

Cost-effectiveness Analysis in R Using a Multi-state Modeling Survival Analysis Framework: A Tutorial. 2017

Detection in blood of autoantibodies to tumour antigens as a case-finding method in lung cancer using the EarlyCDT®-Lung Test (ECLS): study protocol for a randomized controlled trial. 2017

Development of the Galaxy Chronic Obstructive Pulmonary Disease (COPD) Model Using Data from ECLIPSE: Internal Validation of a Linked-Equations Cohort Model 2017

The International Decision Support Initiative Reference Case for Economic Evaluation: An Aid to Thought 2016

 A View from the Bridge: Health Economic Evaluation – A Value-Based Framework? 2016

Analyzing Health-Related Quality of Life in the EVOLVE Trial: The Joint Impact of Treatment and Clinical Events 2016

Editorial. 2016

Tools for Economic Analysis of Patient Management Interventions in Heart Failure Cost-Effectiveness Model: A Web-based program designed to evaluate the cost-effectiveness of disease management programs in heart failure 2016

Close Contact Casting vs Surgery for Initial Treatment of Unstable Ankle Fractures in Older Adults: A Randomized Clinical Trial 2016

The SCottish Alcoholic Liver disease Evaluation: A Population-Level Matched Cohort Study of Hospital-Based Costs, 1991-2011. 2016

Patient Heterogeneity in Health Economic Decision Models for Chronic Obstructive Pulmonary Disease: Are Current Models Suitable to Evaluate Personalized Medicine? 2016

Unrelated Future Costs and Unrelated Future Benefits: Reflections on NICE Guide to the Methods of Technology Appraisal 2016

Estimating Health-State Utility for Economic Models in Clinical Studies: An ISPOR Good Research Practices Task Force Report 2016

Determination of the most appropriate method for extrapolating overall survival data from a placebo-controlled clinical trial of lenvatinib for progressive, radioiodine-refractory differentiated thyroid cancer 2016

A cardiovascular disease policy model: part 2-preparing for economic evaluation and to assess health inequalities 2016

Spacing Pregnancies Appropriately: Long-Acting Reversible Contraception in the Immediate Postpartum Period. 2016

Operationalising the capability approach as an outcome measure in public health: The development of the OCAP-18 2015

Decision analytic cost-effectiveness model to compare prostate cryotherapy to androgen deprivation therapy for treatment of radiation recurrent prostate cancer. 2015

Hospital Expenditure at the End-of-Life: What Are the Impacts of Health Status and Health Risks? 2015

A cardiovascular disease policy model that predicts life expectancy taking into account socioeconomic deprivation. 2015

Temporal trends and risk factors for readmission for infections, gastrointestinal and immobility complications after an incident hospitalisation for stroke in Scotland between 1997 and 2005. 2015

The progressivity of health-care financing in Kenya. 2014

Methods for Specifying the Target Difference in a Randomised Controlled Trial: The Difference ELicitation in TriAls (DELTA) Systematic Review. 2014

Assessing methods to specify the target difference for a randomised controlled trial: DELTA (Difference ELicitation in TriAls) review. 2014

Projecting long-term graft and patient survival after transplantation. 2014

Questionnaire to assess relevance and credibility of modeling studies for informing health care decision making: an ISPOR-AMCP-NPC Good Practice Task Force report. 2014

Statistical Issues in Economic Evaluations. 2014

Population ageing and healthcare expenditure projections: new evidence from a time to death approach. 2013

A patient-centred approach to estimate total annual healthcare cost by body mass index in the UK Counterweight programme. 2013

How effective is the Forestry Commission Scotland’s woodland improvement programme–‘Woods In and Around Towns’ (WIAT)–at improving psychological well-being in deprived urban communities? A quasi-experimental study. 2013

Time trends in 30 day case-fatality following hospitalisation for asthma in adults in Scotland: a retrospective cohort study from 1981 to 2009. 2013

Prognosis Research Strategy (PROGRESS) 2: prognostic factor research. 2013

Assessing the impact of state “opt-out” policy on access to and costs of surgeries and other procedures requiring anesthesia services. 2017

Outcomes of Surgeries Performed in Physician Offices Compared With Ambulatory Surgery Centers and Hospital Outpatient Departments in Florida. 2017

Economic evaluation of procalcitonin-guided antibiotic therapy in acute respiratory infections: a Chinese hospital system perspective. 2017

Cost impact of unexpected disposition after orthopedic ambulatory surgery associated with category of anesthesia provider. 2016

In-office magnetic resonance imaging (MRI) equipment ownership and MRI volume among Medicare patients in orthopedic practices. 2015

The Economics Of Critical Care Diagnostics: The Case Of Procalcitonin-Guided Care In Treatment Of Acute Respiratory Infection In The U.S. 2015

Economic evaluation of procalcitonin-guided antibiotic therapy in acute respiratory infections: a US health system perspective. 2015

Can Improved Treatment of Allergic Rhinitis Improve Workplace Productivity? The Role of Intranasal Formulation of Azelastine Hydrochloride and Fluticasone Propionate (Dymista). 2014

Organizational boundaries of medical practice: the case of physician ownership of ancillary services. 2012

Tobacco litter costs and public policy: a framework and methodology for considering the use of fees to offset abatement costs. 2011

Effects of health savings account-eligible plans on utilization and expenditures. 2011

Converting to critical access status: how does it affect rural hospitals’ financial performance? 2009

Factors associated with Iowa rural hospitals’ decision to convert to critical access hospital status. 2009

Cost effectiveness of a point-of-care test for adenoviral conjunctivitis. 2008

The economics of specialty hospitals. 2008

Effects of specialty hospitals on the financial performance of general hospitals, 1997-2004. 2007

Effect of critical access hospital conversion on patient safety. 2007

Clinical practice guidelines and organizational adaptation: a framework for analyzing economic effects. 2006

Implementation of hospital computerized physician order entry systems in a rural state: feasibility and financial impact. 2005

What would be the effect of referral to high-volume hospitals in a largely rural state? 2004

Post-acute care for children with special health care needs. 2018

Assessing the impact of state “opt-out” policy on access to and costs of surgeries and other procedures requiring anesthesia services. 2017

Potentially Preventable Hospitalizations and the Burden of Healthcare-Associated Infections. 2017

Cost impact of unexpected disposition after orthopedic ambulatory surgery associated with category of anesthesia provider. 2017

Hospital Characteristics are Associated With Readiness to Attain Stage 2 Meaningful Use of Electronic Health Records. 2017

Outcomes of Surgeries Performed in Physician Offices Compared With Ambulatory Surgery Centers and Hospital Outpatient Departments in Florida. 2017

Trends in Hospitalization of Older Adults with Traumatic Brain Injury. 2016

Women, family medicine, and career choice: An opportunity cost analysis. 2016

In-office magnetic resonance imaging (MRI) equipment ownership and MRI volume among Medicare patients in orthopedic practices. 2015

Do rural and urban women experience differing rates of maternal rehospitalizations? 2015

Is diabetes color-blind? Growth of prevalence of diagnosed diabetes in children through 2030. 2015

Economic evaluation of procalcitonin-guided antibiotic therapy in acute respiratory infections: a US health system perspective. 2015

Patterns of onsite magnetic resonance imaging equipment among orthopedic practices. 2015

Can an Internet-based health risk assessment highlight problems of heart disease risk factor awareness? A cross-sectional analysis. 2014

Effects of diabetes self-management programs on time-to-hospitalization among patients with type 2 diabetes: a survival analysis model. 2014

Can chronic disease management programs for patients with type 2 diabetes reduce productivity-related indirect costs of the disease? Evidence from a randomized controlled trial. 2014

Squeezing the balloon: propensity scores and unmeasured covariate balance. 2013

Medicare Advantage Reimbursement to Physicians. 2017

Association of Reference Pricing with Drug Selection and Spending. 2017

Value-Based Physician Payment in Oncology: Public and Private Insurer Initiatives. 2017

Reference Pricing Changes The ‘Choice Architecture’ Of Health Care For Consumers. 2017

Reference Pricing, Consumer Cost-Sharing, and Insurer Spending for Advanced Imaging Tests. 2016

Association of Reference Pricing for Diagnostic Laboratory Testing With Changes in Patient Choices, Prices, and Total Spending for Diagnostic Tests. 2016

Reference Pricing with Endogenous or Exogenous Payment Limits: Impacts on Insurer and Consumer Spending. 2016

Association of Reference Payment for Colonoscopy With Consumer Choices, Insurer Spending, and Procedural Complications. 2015

Consumer Choice Between Hospital-Based and Freestanding Facilities for Arthroscopy: Impact on Prices, Spending, and Surgical Complications. 2015

Reference-based benefit design changes consumers’ choices and employers’ payments for ambulatory surgery. 2015

US hospital payment adjustments for innovative technology lag behind those in Germany, France, and Japan. 2015

Biomedical innovation in the era of health care spending constraints. 2015

Total expenditures per patient in hospital-owned and physician-owned physician organizations in California. 2014

Specialty pharmaceuticals: policy initiatives to improve assessment, pricing, prescription, and use. 2014

Quantifying opportunities for hospital cost control: medical device purchasing and patient discharge planning. 2014

Increases in consumer cost sharing redirect patient volumes and reduce hospital prices for orthopedic surgery. 2013

Consumer cost sharing and use of biopharmaceuticals for rheumatoid arthritis. 2013

Case studies of orthopedic surgery in California: the virtues of care coordination versus specialization. 2013

Antibiotic strategies in critical care: back to square one? 2018

Markers of Neutrophil Extracellular Traps Predict Adverse Outcome in Community-Acquired Pneumonia: Secondary Analysis of a Randomised Controlled Trial. 2018

Procalcitonin Testing to Guide Antibiotic Therapy in Acute Upper and Lower Respiratory Tract Infections. 2018

Management and prevention of refeeding syndrome in medical inpatients: An evidence-based and consensus-supported algorithm. 2018

Association of adrenal hormone metabolites and mortality over a 6-year follow-up in COPD patients with acute exacerbation. 2018

Optimization of nutrition during allogeneic hematologic stem cell transplantation. 2018

Prediction of post-acute care demand in medical and neurological inpatients: diagnostic assessment of the post-acute discharge score – a prospective cohort study. 2018

Copeptin levels and commonly used laboratory parameters in hospitalised patients with severe hypernatraemia – the “Co-MED study”. 2018

Reassessment of a meta-analysis of procalcitonin-guided antibiotic therapy for lower respiratory tract infections – Authors’ reply. 2018

The role of metabolomic markers for patients with infectious diseases: implications for risk stratification and therapeutic modulation. 2018

Mortality due to refeeding syndrome? You only find what you look for, and you only look for what you know. 2018

Effect of preoperative immunonutrition on postoperative short-term outcomes of patients with head and neck squamous cell carcinoma. 2018

Biological pathways underlying the association of red cell distribution width and adverse clinical outcome: Results of a prospective cohort study. 2018

Gut, microbiota-dependent trimethylamine-N-oxide is associated with long-term all-cause mortality in patients with exacerbated chronic obstructive pulmonary disease. 2018

ESPEN guidelines on nutritional support for polymorbid internal medicine patients. 2018

Do you want to participate in a clinical study as a healthy control? – Risk or benefit? 2017

Efficacy and Safety of Procalcitonin Guidance in Patients With Suspected or Confirmed Sepsis: A Systematic Review and Meta-Analysis. 2017

Management of Respiratory Infections with Use of Procalcitonin: Moving toward More Personalized Antibiotic Treatment Decisions. 2017

Asymmetric Dimethylarginine Predicts Long-Term Outcome in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease. 2017

Copeptin for risk stratification in non-traumatic headache in the emergency setting: a prospective multicenter observational cohort study. 2017

The TRIAGE-ProADM Score for an Early Risk Stratification of Medical Patients in the Emergency Department – Development Based on a Multi-National, Prospective, Observational Study. 2017

Innovative transition interventions to better align healthcare needs in hospitalised medical patients. 2017

Comparative quality measures of emergency care: an outcome cockpit proposal to survey clinical processes in real life. 2017

Procalcitonin to initiate or discontinue antibiotics in acute respiratory tract infections. 2017

Are admission procalcitonin levels universal mortality predictors across different medical emergency patient populations? Results from the multi-national, prospective, observational TRIAGE study. 2017

Is Graves’ disease a primary immunodeficiency? New immunological perspectives on an endocrine disease. 2017

Procalcitonin-guided antibiotic stewardship from newborns to centennials. 2017

DIAGNOSTIC ACCURACY OF BASAL CORTISOL LEVEL TO PREDICT ADRENAL INSUFFICIENCY IN COSYNTROPIN TESTING: RESULTS FROM AN OBSERVATIONAL COHORT STUDY WITH 804 PATIENTS. 2017

Personalized medicine of patients with respiratory infections through the measurement of specific blood biomarkers: fact or fiction? 2017

The natriuretic peptide MR-proANP predicts all-cause mortality and adverse outcome in community patients: a 10-year follow-up study. 2017

Peripheral monocytosis as a predictive factor for adverse outcome in the emergency department: Survey based on a register study. 2017

Pro-Adrenomedullin predicts 10-year all-cause mortality in community-dwelling patients: a prospective cohort study. 2017

New data about semicircular canal morphology and locomotion in modern hominoids. 2017

Overview of procalcitonin assays and procalcitonin-guided protocols for the management of patients with infections and sepsis. 2017

Activation of the Serotonin Pathway is Associated with Poor Outcome in COPD Exacerbation: Results of a Long-Term Cohort Study. 2017

Activation of the tryptophan/serotonin pathway is associated with severity and predicts outcomes in pneumonia: results of a long-term cohort study. 2017

Residual confounding or lack of effect? 2017

Interleukin-1 Antagonism Decreases Cortisol Levels in Obese Individuals. 2017

Serial Procalcitonin Predicts Mortality in Severe Sepsis Patients: Results From the Multicenter Procalcitonin MOnitoring SEpsis (MOSES) Study. 2017

External validation of the GREAT score to predict relapse risk in Graves’ disease: results from a multicenter, retrospective study with 741 patients. 2017

Industry sponsorship and outcomes of nutrition studies: Is there an association when looking at the trial level? 2017

Procalcitonin as preoperative marker for surgery in advanced parapneumonic empyema. 2017

Time-dependent association of glucocorticoids with adverse outcome in community-acquired pneumonia: a 6-year prospective cohort study. 2017

Nutritional support practices in hematopoietic stem cell transplantation centers: A nationwide comparison. 2017

Revisiting the refeeding syndrome: Results of a systematic review. 2017

Metformin prevents metabolic side effects during systemic glucocorticoid treatment. 2017

Economic evaluation of procalcitonin-guided antibiotic therapy in acute respiratory infections: a Chinese hospital system perspective. 2017

Evaluation of copeptin and commonly used laboratory parameters for the differential diagnosis of profound hyponatraemia in hospitalized patients: ‘The Co-MED Study’. 2017

Food for thought: why does the medical community struggle with research about nutritional therapy in the acute care setting? 2017

Effect of procalcitonin-guided antibiotic treatment on mortality in acute respiratory infections: a patient level meta-analysis. 2017

Serial Procalcitonin as a Predictor of Bacteremia and Need for Intensive Care Unit Care in Adults With Pneumonia, Including Those With Highest Severity: A Prospective Cohort Study. 2017

Admission levels of asymmetric and symmetric dimethylarginine predict long-term outcome in patients with community-acquired pneumonia. 2017

Procalcitonin-guided diagnosis and antibiotic stewardship revisited. 2017

Additional Real-World Evidence Supporting Procalcitonin as an Effective Tool to Improve Antibiotic Management and Cost of the Critically Ill Patient. 2017

Can we predict relapse in Graves’ disease? Results from a systematic review and meta-analysis. 2017

Obesity paradox in patients with community-acquired pneumonia: Is inflammation the missing link? 2017

Characteristics and outcomes of patients with profound hyponatraemia due to primary polydipsia. 2017

Benefit of adjunct corticosteroids for community-acquired pneumonia in diabetic patients. 2016

Long-term outcome of profound hyponatremia: a prospective 12 months follow-up study. 2016

Trimethylamine-N-oxide (TMAO) predicts fatal outcomes in community-acquired pneumonia patients without evident coronary artery disease. 2016

Procalcitonin: A new biomarker for the cardiologist. 2016

Prospective evaluation of biomarkers for prediction of quality of life in community-acquired pneumonia. 2016

Copeptin predicts 10-year all-cause mortality in community patients: a 10-year prospective cohort study. 2016

Pathogen- and antibiotic-specific effects of prednisone in community-acquired pneumonia. 2016

Influence of hospital characteristics on quality of care in patients with community-acquired pneumonia. 2016

The National Early Warning Score (NEWS) for outcome prediction in emergency department patients with community-acquired pneumonia: results from a 6-year prospective cohort study. 2016

Association of Nutritional Parameters with Clinical Outcomes in Patients with Acute Myeloid Leukemia Undergoing Haematopoietic Stem Cell Transplantation. 2016

Psychological distress in medical patients 30 days following an emergency department admission: results from a prospective, observational study. 2016

Psychological distress in medical patients seeking ED care for somatic reasons: results of a systematic literature review. 2016

Detection and treatment of medical inpatients with or at-risk of malnutrition: Suggested procedures based on validated guidelines. 2016

Das «Refeeding-Syndrom» beim internistischen Patienten. 2016

Procalcitonin in critically ill patients: time to change guidelines and antibiotic use in practice. 2016

Does Immunosuppressive Therapy Improve Outcomes in Graves’ Disease? A Systematic Review and Meta-Analysis. 2016

Vitamin D Deficiency Strongly Predicts Adverse Medical Outcome Across Different Medical Inpatient Populations: Results From a Prospective Study. 2016

Predictors for Delayed Emergency Department Care in Medical Patients with Acute Infections – An International Prospective Observational Study. 2016

Comparison between B·R·A·H·M·S PCT direct, a new sensitive point-of-care testing device for rapid quantification of procalcitonin in emergency department patients and established reference methods – a prospective multinational trial. 2016

Infection biomarkers in primary care patients with acute respiratory tract infections-comparison of Procalcitonin and C-reactive protein. 2016

Unraveling the Link between Malnutrition and Adverse Clinical Outcomes: Association of Acute and Chronic Malnutrition Measures with Blood Biomarkers from Different Pathophysiological States. 2016

Procalcitonin (PCT) levels for ruling-out bacterial coinfection in ICU patients with influenza: A CHAID decision-tree analysis. 2016

Nutritional Support and Outcomes in Malnourished Medical Inpatients: A Systematic Review and Meta-analysis. 2016

Screening and Treatment of Vitamin D Deficiency on Hospital Admission: Is There a Benefit for Medical Inpatients? 2016

The utility of proadrenomedullin and procalcitonin in comparison to C-reactive protein as predictors of sepsis and bloodstream infections in critically ill patients with cancer*. 2015

Can We Reduce Negative Blood Cultures With Clinical Scores and Blood Markers? Results From an Observational Cohort Study. 2015

Midregional Proadrenomedullin Improves Risk Stratification beyond Surgical Risk Scores in Patients Undergoing Transcatheter Aortic Valve Replacement. 2015

Association of nutritional risk and adverse medical outcomes across different medical inpatient populations. 2015

Biomarkers from distinct biological pathways improve early risk stratification in medical emergency patients: the multinational, prospective, observational TRIAGE study. 2015

Systematic review regarding metabolic profiling for improved pathophysiological understanding of disease and outcome prediction in respiratory infections. 2015

Corticosteroid therapy for pneumonia – Author’s reply. 2015

Procalcitonin: An Effective Screening Tool and Safe Therapeutic Decisionmaking Aid for Emergency Department Patients With Suspected Sepsis. 2015

Use of procalcitonin, C-reactive protein and white blood cell count to distinguish between lower limb erysipelas and deep vein thrombosis in the emergency department: A prospective observational study. 2015

The Reply. 2015

Prospective analysis of adrenal function in patients with acute exacerbations of COPD: the Reduction in the Use of Corticosteroids in Exacerbated COPD (REDUCE) trial. 2015

Postoperative Copeptin Concentration Predicts Diabetes Insipidus After Pituitary Surgery. 2015

Procalcitonin and pyuria-based algorithm reduces antibiotic use in urinary tract infections: a randomized controlled trial. 2015

Performance of the Manchester Triage System in Adult Medical Emergency Patients: A Prospective Cohort Study. 2015

“Eat your lunch!” – controversies in the nutrition of the acutely, non-critically ill medical inpatient. 2015

Prognostic value of procalcitonin in respiratory tract infections across clinical settings. 2015

Procalcitonin improves the Glasgow Prognostic Score for outcome prediction in emergency patients with cancer: a cohort study. 2015

“Personalized” sepsis care with the help of specific biomarker levels on admission and during follow up: are we there yet? 2015

Symptoms and characteristics of individuals with profound hyponatremia: a prospective multicenter observational study. 2015

Economic evaluation of procalcitonin-guided antibiotic therapy in acute respiratory infections: a US health system perspective. 2015

Utility of procalcitonin, C-reactive protein and white blood cells alone and in combination for the prediction of clinical outcomes in community-acquired pneumonia. 2015

Biomarker-guided personalised emergency medicine for all – hope for another hype? 2015

[Laboratory results in clinical practice: importance of interpretation in the clinical context]. 2015

Adjunct prednisone therapy for patients with community-acquired pneumonia: a multicentre, double-blind, randomised, placebo-controlled trial. 2015

Copeptin as a stress marker prior and after a written examination–the CoEXAM study. 2015

The prognostic blood biomarker proadrenomedullin for outcome prediction in patients with chronic obstructive pulmonary disease (COPD): a qualitative clinical review. 2015

Copeptin concentrations during psychological stress: the PsyCo study. 2014

Pre-analytic factors and initial biomarker levels in community-acquired pneumonia patients. 2014

Copeptin for the prediction of recurrent cerebrovascular events after transient ischemic attack: results from the CoRisk study. 2014

Ruling out Legionella in community-acquired pneumonia. 2014

The role of immune and metabolic biomarkers for improved management of sepsis patients. 2014

Excluding infection through procalcitonin testing improves outcomes of congestive heart failure patients presenting with acute respiratory symptoms: results from the randomized ProHOSP trial. 2014

BNP but Not s-cTnln is associated with cardioembolic aetiology and predicts short and long term prognosis after cerebrovascular events. 2014

Long-term Prognosis in COPD Exacerbation: Role of Biomarkers, Clinical Variables and Exacerbation Type. 2014

Corticosteroid treatment for community-acquired pneumonia–the STEP trial: study protocol for a randomized controlled trial. 2014

Head-to-head comparison of length of stay, patients’ outcome and satisfaction in Switzerland before and after SwissDRG-Implementation in 2012 in 2012: an observational study in two tertiary university centers. 2014

Association of adrenal function and disease severity in community-acquired pneumonia. 2014

Neither ibuprofen nor steam improves symptom control compared with paracetamol in patients with acute respiratory tract infections in primary care. 2014

Effectiveness of Proadrenomedullin Enhanced CURB65 Score Algorithm in Patients with Community-Acquired Pneumonia in “Real Life”, an Observational Quality Control Survey. 2014

Effect of hyperglycaemia on inflammatory and stress responses and clinical outcome of pneumonia in non-critical-care inpatients: results from an observational cohort study. 2014

Biomarker-guided de-escalation of empirical therapy is associated with lower risk for adverse outcomes. 2014

Interaction improves perception of gloss. 2013

Hyponatremia and anti-diuretic hormone in Legionnaires’ disease. 2013

Using procalcitonin-guided algorithms to improve antimicrobial therapy in ICU patients with respiratory infections and sepsis. 2013

Biomarker-enhanced triage in respiratory infections: a proof-of-concept feasibility trial. 2013

Procalcitonin guidance to reduce antibiotic treatment of lower respiratory tract infection in children and adolescents (ProPAED): a randomized controlled trial. 2013

Procalcitonin to initiate or discontinue antibiotics in acute respiratory tract infections. 2013

Optimizing triage and hospitalization in adult general medical emergency patients: the triage project. 2013

Procalcitonin decrease over 72 hours in US critical care units predicts fatal outcome in sepsis patients. 2013

Short-term vs conventional glucocorticoid therapy in acute exacerbations of chronic obstructive pulmonary disease: the REDUCE randomized clinical trial. 2013

Biomarkers of endothelial cell activation in early sepsis. 2013

Head-to-head comparison of fee-for-service and diagnosis related groups in two tertiary referral hospitals in Switzerland: an observational study. 2013

Prognostic value of dehydroepiandrosterone-sulfate and other parameters of adrenal function in acute ischemic stroke. 2013

Streamlining antibiotic therapy with procalcitonin protocols: consensus and controversies. 2013

Copeptin adds prognostic information after ischemic stroke: results from the CoRisk study. 2013

Blood biomarkers for personalized treatment and patient management decisions in community-acquired pneumonia. 2013

Procalcitonin, pyuria and proadrenomedullin in the management of urinary tract infections–‘triple p in uti’: study protocol for a randomized controlled trial. 2013

Diabetic status and the relation of the three domains of glycemic control to mortality in critically ill patients: an international multicenter cohort study. 2013

It Is all about risk-adapted algorithms. 2013

Clinical outcomes associated with procalcitonin algorithms to guide antibiotic therapy in respiratory tract infections. 2013

Antibiotics for non-pneumonic respiratory-tract infections. 2013